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In a cultured cell model, AHCY pharmacological inhibition led to reduced cap methylation and synthesis of polyadenylated RNA, implicating AHCY in both cap methylation of pre-mRNA and transcriptional elongation processes (62)

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0.22 µm) immediately prior to use Aliquot and store reconstituted solutions at –20 °C (or lower) to minimise degradation Avoid repeated freeze–thaw cycles Specifications Summary Precautions & Notes Experimental behaviour of IGF-1 LR3 is influenced by receptor expression, concentration, and exposure duration Modified IGF-1 analogues may exhibit signalling profiles distinct from native IGF-1 Buffer composition, pH, and ionic strength may affect peptide stability and assay performance Appropriate controls are recommended to distinguish specific from non-specific effects Intended strictly for laboratory research use