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In addition, experimental pathology led to the activation of free radical processes, as evidenced by a decrease in the reserves of reduced glutathione, the main antioxidant factor of cells and an increase in the concentration of MDA, the main marker of oxidative stress in rat brain homogenates, against the background of a decrease in the levels of SOD activity (superoxide is one of the main active forms of oxygen in the cell, and SOD plays a key role as an antioxidant) and catalase (p 0.05 in each case), which indicates the ability of the drug Cortexin ® to activate antioxidant defense mechanisms in conditions of tissue hypoxia
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