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Altered lymphocyte apoptosis in patients with SLE could contribute to an overload of nucleosome in circulation that could initiate an autoimmune response that might break tolerance, resulting in the autoimmune phenomena
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6.2.3.2 Myelin vacuolization and demyelination N₂O-induced Vit B12 inactivation results in MMA accumulation (Hathout and El-Saden, 2011), altering lipid composition in myelin membranes and destabilizing their structure (Agamanolis et al., 1978)
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