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However, in IBD the balance between these two populations is disrupted, with a reduction in tissue resident macrophages and an increase in infiltrating macrophages, which have a more pro-inflammatory phenotype [3,4,5]
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Per accedere alla matrice mitocondriale, gli acidi grassi di lunghezza pari o superiore a 14 atomi di carbonio, per la β (beta) ossidazione e la produzione di ATP, devono essere attivati e successivamente trasportati mediante tre reazioni enzimatiche dello shuttle della carnitina
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