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⸻ The FY26 cycle is structured in three stages: PRE-RELEASE During this phase, companies can: * review topics early * communicate directly with topic authors * ask technical and mission-related questions before proposals officially open For Release 1: * Pre-Release opened: April 13, 2026 * Open phase begins: May 6, 2026 * Final submission deadline: June 3, 2026 ⸻ OPEN Once the solicitation officially opens: * proposals can be submitted through DSIP * questions must go through the DSIP Topic Q&A system * direct communication with topic authors is no longer permitted At that point, the process changes from exploration to competition

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however, most clinical studies and meta-analyses have not controlled for various confounding factors, such as dose, duration, and type of PPI exposure, the inclusion and exclusion criteria were also insufficiently stringent across these studies

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