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Nevertheless, when considering the external supply of inositols in the brain, it should be considered that the administration of inositol derivatives like SI decreases the concentration of MI, which may represent a shift in the inositol equilibrium, promoting MI degradation to stabilize brain homeostasis [18]
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Related to this issue of what are correct absolute amounts for rates of GSH conjugation is the question of how interindividual variations in metabolism in humans, such as those due to genetic polymorphisms or developmental differences, may contribute to rates of metabolism and the consequent nephrotoxicity
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