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Tendon and ligament models — fibroblast outgrowth, migration and survival under stress Collagen biology — deposition, cross-linking and organisation during experimental healing Angiogenesis — endothelial tube formation and blood-flow recovery in ischaemia models Nitric-oxide signalling — interaction with eNOS activity and vascular tone Gastrointestinal mucosa — protective effects in ulcer and colitis models Neurovascular and muscle injury models — functional recovery endpoints Scientific context and proposed mechanisms In tendon cell models, BPC-157 has been associated with increased fibroblast migration and spreading, with authors linking the effect to activation of the FAK–paxillin signalling pathway involved in cell adhesion and movement

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[DOI] [PubMed] [Google Scholar] 16.Krivic A., Anic T., Seiwerth S., Huljev D., Sikiric P