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Furthermore, studies indicate that inhibition of the PI3K/AKT/mTOR pathway enhances melanoma cell sensitivity to the chemotherapy drug temozolomide (TMZ), suggesting that combining bee venom with TMZ could lead to a more potent inhibitory effect on melanoma (Sinnberg et al., 2009

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Experimental studies have shown that low glutathione levels lead to poor liver and kidney function, and result in unnecessarily large quantities of toxins