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These trials should prioritize determining the optimal dosages, administration protocols and the effects of combination therapies
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JAM-A are concentrated at epithelial and endothelial TJs, and the extracellular N-terminal domains bind to ligands through hemophilic (formation of TJs and bicellular border) and heterophilic interactions (Fan et al., 2019)
These statements have not been evaluated by the Food and Drug Administration (FDA)
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