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Keywords Carbamazepine Trade Name: generic, Carbatrol, Equetro, Tegretol ยฎ Drug Class: antiepileptic Mechanism of Action: blocks Na+ channels (similar to phenytoin) Indications: management of partial seizures & tonic-clonic seizures treatment of the pain associated with true trigeminal neuralgia Contraindications: should not be administered to patients with a history of hepatic disease, AV heart block, or using MAO inhibitor Side Effects: idiosyncratic blood dyscrasias BLACK BOX WARNING: Stevens-Johnson syndrome BLACK BOX WARNING: aplastic anemia & agranulocytosis (very rare) diplopia ataxia Pharmacokinetics: carbamazepine undergoes hepatic metabolism to multiple metabolites
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