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As with skin, the honest patient conversation centers on timeline: regenerative and remodeling effects unfold over months and a hair cycle, not weeks, and expectation-setting at the first consultation is most of the clinical work

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Since participants in the present study were high functioning and demonstrated rather mild symptoms, they may have been in a functionally compensated state, in comparison to the patients studied in clinical settings in previous MRS [22,24] and post-mortem [25] studies, where decreased GSH was observed