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Further research is needed to define subgroups of children with ASD in which these treatments may be most effective as well as confirm their efficacy in DBPC, large-scale multicenter studies

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Basics of the TGF-β Signaling Pathway Based on the similarities in protein sequence and structure, the mammalian TGF-β members, with a few exceptions, can be classified into three major groups: the TGF-β family, the inhibin/activin family and the BMP (bone morphogenic protein)/GDF (growth and differentiation factor) family (Morikawa et al., 2016)