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Norepinephrine: Focus, stress, genetics, and brain function
In AML-12 cells, we found that exogenous PE (18:0/18:1) not only markedly up-regulated the expression of BAX, caspase-9 and caspase-3, but also led to significant down-regulation of BCL2 protein, which suggested that accumulation of PEs might cause apoptosis of hepatocytes
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