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Diabetologia (2001) 44(3):325–32
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In the fetal brain activation of the MT1/MT2 receptors by melatonin upregulates the expression of growth factors like brain-derived neurotrophic factor (BDNF) and glial cell-derived neurotrophic factor (GDNF) in neuronal stem cells [152], [153] stimulating their proliferation and differentiation [154], [155], [156], as well as promotes neuronal myelination, neuronal plasticity, migration and dendrite formation [155], [157](Fig
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