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The compound has been investigated in preclinical research for adipocyte biology, fatty acid oxidation, lipolysis pathways, cartilage biology, and metabolic energy expenditure across both cell-culture and rodent obesity research models
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Another target of pJNK phosphorylation in the mouse turns out to be the catalytic subunit of glutamate-cysteine ligase (GCLC), the rate-limiting enzyme of the gamma-glutamyl cycle that is responsible for GSH synthesis
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