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Mice were housed and bred in the Weill Cornell Medicine animal facility

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Although myeloablation can be ameliorated by bone marrow transplant or compensated by only looking at an earlier survival time point, more recent rodent models have employed partial body shielding, which spares enough bone marrow to allow the immune system to provide some level of protection against infection and hemorrhage, and to accelerate immune reconstitution ( The role of infection due to bacterial translocation from the gut has long been a recognized consequence of ionizing radiation in mammals