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CTLA-4 binds to the CD80 and CD86 ligands on antigen presenting cells outcompeting CD28 mediated activating signals which downregulates the immune response by inhibiting T cell activation
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[DOI] [PubMed] [Google Scholar] 165.Melis G.C., ter Wengel N., Boelens P.G., van Leeuwen P.A
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