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NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress | bioRxiv
One example is shown in a 2003 study by Pavlidis and colleagues (Figure 6) (9)
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Typically, α-synuclein localizes to the mitochondria-associated membrane, and its presence may disrupt mitochondrial function by promoting the formation of the mitochondrial permeability transition pore (mPTP), leading to mitochondrial membrane potential (MMP) loss, subsequent mitochondrial degradation, and ultimately cell death (192)
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