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If you are weighing a compounded peptide against an FDA-approved option, the relevant comparison is rarely “which works better” (we do not make efficacy claims for unapproved substances)

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During B 12 deficiency, the failure of B 12 -dependent methionine biosynthesis leads to the accumulation of Hcy [4], which has pro-oxidant activity [4] and can activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase to generate reactive oxygen species (ROS) [5]