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They found that early intervention in the form of strict control of blood glucose, lipids, and blood pressure, along with correction of dietary habits to control fat intake and long-term physical exercise can improve several indicators of kidney prognosis, including macroalbuminuria, GFR decline rate, ESRD and death [84]
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ROS include the hydroxyl radical (*OH), the superoxide anion radical (O* − ), singlet oxygen, and hydrogen peroxide (H 2 O 2 ), which, as an exception, does not possess an unpaired electron
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