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The exact signals that induce CAC are not entirely known, however, co-culture of lung cancer-derived EVs can promote adipocyte lipolysis through the delivery of IL-6 (215)

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Figure 8 summarizes the main points of this paper, where we claim that excessive levels of deuterium in the mitochondria due to gut dysbiosis may be the driving force that ultimately results in cardiolipin oxidation and migration to the outer membrane, following its accumulation of deuterium bound to the bis-allylic carbon atoms

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