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It also explores specific pathways, including the role of systemic inflammation in BBB disruption and neuroinflammation, the impact of gut microbiota dysbiosis on intestinal permeability and translocation of microbial products, the contribution of oxidative stress to BBB damage, the potential involvement of the vagus nerve in transmitting signals from the gut to the brain, and the effects of altered gut microbial metabolite production on neuronal function
Antixoidants
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Repeated-dose toxicity studies in rats, dogs, and mice for up to 6 weeks across various administration routes showed excellent tolerance with only slight reversible creatinine decreases at high doses
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