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Human-specific sequence features in HTT exon 1 promote toxic misprocessing via splicing factor SRSF7 | Nature Communications
This effect may be attributed to the hydrogen atoms provided by the hydroxyl structure or the electron delocalization effect triggered by conjugation with the oxygen group, which leads to the scavenging of free radicals [51], and the hydroxyl structure of the B ring is the most important factor in determining the clearance of ROS and RNS compared to the A and C rings [54]
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