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The factors which are to be considered for dose estimation by transdermal route are discussed in the literature and are in general as enumerated in table 1 Table 1: Factors for consideration for Transdermal Dose Calculation Thus, dose calculation requires thorough consideration of all above factors
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Juglone is the primary derivative of 1,4-naphthoquinones and 1,2- and 1,4-naphthoquinones, which are toxic metabolites of naphthalene, the major polynuclear aromatic hydrocarbon present in ambient air
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