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Early sleep deprivation symptoms may include: Daytime sleepiness Fatigue Weakness or decreased physical strength Decreased ability to fight infections or getting sick more often Headaches Slowed reactions Difficulty focusing Memory problems Irritability Carbohydrate and sugar cravings Untreated sleep deprivation can lead to severe symptoms down the line, such as: Slurred speech Hand tremors Nystagmus (uncontrolled eye movements) Brief periods of falling asleep throughout the day that only last a few seconds (microsleeps) Ptosis (drooping eyelids) Hallucinations Poor judgment Impulsive behavior Lower pain tolerance Symptoms of depression and anxiety Over time, sleep deprivation can also increase your risk of stroke, asthma, mental health conditions like depression, and sleep disorders like insomnia