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MAChR = Muscarinic Acetylcholine Receptor Existing drugs for clinical use L—DOPA The primary cause of PD is the deficiency of dopamine (DA) in the nigrostriatal pathway
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There is an accumulation of allysine, pipecolic acid, and P6C, which forms inactive complexes with pyridoxal phosphate (vitamin B 6 ) acting as a cofactor of several enzymes, primarily decarboxylases and aminotransferases [36]
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