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HBV can integrate into the host genome or persist as a minichromosome of covalently closed circular DNA (cccDNA) with histone and non-histone proteins (Koumbi and Karayiannis, 2015)
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People with autoimmune disease called atrophic gastritis might not absorb enough Vitamin B12 because they make too little hydrochloric acid and intrinsic factor in their stomach
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