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Receptor ligands such as lectins, toxins, viral haemagglutinins, invasins, transferrin and vitamins (vitamin B12, folate, riboflavin and biotin), can be conjugated or covalently attached to protein or peptide drug to achieve site specific targeting (Lim and Shen, 2005)

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A “síndrome do compartimento” pode se desenvolver nos locais de injeção nos músculos das pernas, causando dormência, coágulos sanguíneos e espasmos musculares que resultam em perda permanente da função