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The short-term data from mice, discussed previously, support the conclusion that an effect on the liver is unlikely to be observed in humans until very high doses are reached

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Figure 6 shows that protein expression levels of p-NF-κB/NF-κB, TNF-α, IL-1β, and IL-6 are significantly elevated in the CuD and CuD + CuSO 4 groups compared to the control group